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Tai Nguyen So - Vietnam National University, Ha Noi - VNU >
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| Title: | Sassafrins A-D, new antimicrobial azaphilones from the fungus Creosphaeria sassafras |
| Authors: | Quang D.N.
Hashimoto T.
Fournier J.
Stadler M.
Radulovic N.
Asakawa Y. |
| Keywords: | Antimicrobial activity
Azaphilone
Creosphaeria sassafras
Fungi
Sassafrin |
| Issue Date: | 2005 |
| Publisher: | Tetrahedron |
| Citation: | Volume 61, Issue 7, Page 1743-1748 |
| Abstract: | Four new azaphilones named sassafrins A-D (1-4) were isolated from the methanol extract of the stromata of the fungus Creosphaeria sassafras (Xylariaceae, Ascomycetes). Their structures were elucidated by 2D NMR, HR-MS, IR, UV and CD spectroscopy. Sassafrin D (4) possesses a novel skeleton and its biosynthetic pathway is also discussed. In addition, all compounds showed broad-spectrum antimicrobial activity. Their apparently unique occurrence in C. sassafras supports the status of this fungus as a member of a distinct genus within the Xylariaceae, coinciding with molecular and morphological traits. © 2004 Elsevier Ltd. All rights reserved. |
| URI: | http://tainguyenso.vnu.edu.vn/jspui/handle/123456789/11703 |
| ISSN: | 404020 |
| Appears in Collections: | Articles of Universities of Vietnam from Scopus
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